N-(Fluoroethyl)(imidazolylphenyl)formamidines. The issue of the active species of mifentidine

DOI: 10.1021/jm00125a006

Source and publish data:

Journal of Medicinal Chemistry p. 957 - 961 (1989)

Update date:2022-08-04

Topics:

Authors:

Donetti Donetti

Cereda Cereda

Ezhaya Ezhaya

Micheletti

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Article abstract of DOI:10.1021/jm00125a006

Three N-fluoroethyl-substituted (imidazolylphenyl)formamidine derivatives, namely, 2-fluoroethyl (3b), 2,2-difluoroethyl (3c), and 2,2,2-trifluoroethyl (3d), were prepared to test the effect of fluorine substitution on basicity and, then on H₂-

Full text of DOI:10.1021/jm00125a006

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