N-(Fluoroethyl)(imidazolylphenyl)formamidines. The issue of the active species of mifentidine

Article abstract of DOI:10.1021/jm00125a006

Three N-fluoroethyl-substituted (imidazolylphenyl)formamidine derivatives, namely, 2-fluoroethyl (3b), 2,2-difluoroethyl (3c), and 2,2,2-trifluoroethyl (3d), were prepared to test the effect of fluorine substitution on basicity and, then on H₂-