Rhodium-Catalyzed Selective C-H Trideuteromethylation of Indole at C7 Position Using Acetic- d6 Anhydride

DOI: 10.1021/acs.joc.9b01114

Source and publish data:

Journal of Organic Chemistry p. 12764 - 12772 (2019)

Update date:2022-08-02

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Authors:

Han, Xiaowei

Yuan, Yu

Shi, Zhuangzhi

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Article abstract of DOI:10.1021/acs.joc.9b01114

Rhodium-catalyzed C7-selective decarbonylative trideuteromethylation of indoles with commercially available Ac₂O-d₆ via C-H and C-C bond activation has been developed. The key to the high reactivity and regioselectivity of this trans

Full text of DOI:10.1021/acs.joc.9b01114

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