
Journal of Medicinal Chemistry p. 812 - 817 (1975)
Update date:2022-08-05
Topics:
Lee
Ibuka
Kim
Vestal
Hall
Huang
Several novel steroidal α methylene γ lactones and related derivatives have been synthesized as potential steroid alkylating antitumor agents. The synthesis of these compounds involved the convenient Reformatsky type reaction between ethyl α (bromomethyl)
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Doi:10.1021/jo01060a622
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