
Journal of Medicinal Chemistry p. 812 - 817 (1975)
Update date:2022-08-05
Topics:
Lee
Ibuka
Kim
Vestal
Hall
Huang
Several novel steroidal α methylene γ lactones and related derivatives have been synthesized as potential steroid alkylating antitumor agents. The synthesis of these compounds involved the convenient Reformatsky type reaction between ethyl α (bromomethyl)
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(2007)Doi:10.1016/S0008-6215(00)84273-1
(1975)Doi:10.1021/j100239a015
(1983)Doi:10.1002/hlca.19750580329
(1975)Doi:10.1016/j.bmcl.2009.11.029
(2010)