Antitumor agents. 16. Steroidal α methylene γ lactones

DOI: 10.1021/jm00242a010

Source and publish data:

Journal of Medicinal Chemistry p. 812 - 817 (1975)

Update date:2022-08-05

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Authors:

Lee Lee

Ibuka Ibuka

Kim Kim

Vestal Vestal

Hall Hall

Huang Huang

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Article abstract of DOI:10.1021/jm00242a010

Several novel steroidal α methylene γ lactones and related derivatives have been synthesized as potential steroid alkylating antitumor agents. The synthesis of these compounds involved the convenient Reformatsky type reaction between ethyl α (bromomethyl)

Full text of DOI:10.1021/jm00242a010

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