VILSMEIER REAGENTS: PREPARATION OF β-HALO-α,β-UNSATURATED KETONES

Article abstract of DOI:10.1016/S0040-4039(01)80646-8

A new method for the preparation of β-chloro and β-bromo-α,β-unsaturated ketones from β-diketones is described.Utilizing Vilsmeier reagents (prepared from N,N-dimethylformamide and oxalyl chloride or oxalyl bromide) β-halo-α,β-unsaturated ketones are isolated in excellent yields.