European Journal of Medicinal Chemistry p. 441 - 445 (1994)
Update date:2022-08-03
Topics:
Monge
Narro
Martinez-Crespo
Lopez de Cerain
Hamilton
Barker
The nitroacridine derivative 9-[3-(N,N-dimethylamino)propylamino]- 1-nitroacridine (nitracrine) is a potent hypoxia-selective cytotoxin for tumor cells in culture. Modifications of the acridine ring result in altered DNA binding properties. This has sugge
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