Journal of Pharmaceutical Sciences p. 1943 - 1949 (1975)
Update date:2022-08-05
Topics:
Traxler
Moats
Lira
Huffman
The syntheses of seven anthracene amino alcohols with one, two, or three additional substituents are described. These compounds include three 1 aminoethanols, two 9 aminoethanols, and two 9 aminopropanols, prepared from substituted anthraquinones or from 10 chloro 9 anthraldehydes. The antimalarial activity of these compounds, as well as tentative structure activity relationships, is discussed in the light of previously published work.
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