Journal of Medicinal Chemistry p. 555 - 560 (1988)
Update date:2022-07-29
Topics:
Zimmerman, Dennis M.
Cantrell, Buddy E.
Swartzendruber, John K.
Jones, Noel D.
Mendelson, Laura G.
et al.
A respresentative series of N-substituted derivatives of the morphine-based trans-4a-aryldecahydroisoquinoline were synthesized and evaluated for opioid analgesic activities.Compounds with potent analgesic activity and high affinities for the μ and κ opio
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