
Tetrahedron Letters p. 6201 - 6204 (2006)
Update date:2022-08-05
Topics:
Ha, Jae Du
Lee, Su Jung
Nam, So Yeun
Kang, Seung Kyu
Cho, Seung Yoon
Ahn, Jin Hee
Choi, Joong-Kwon
A simple method of synthesizing various 2-imidazol-2-ylacetates is described. Condensation of α-aminoketals with imidates, followed by cyclization in refluxing 4 M-HCl/Dioxane, yielded 2-imidazol-2-ylacetates under one-pot and mild reaction conditions.
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