Bioorganic and Medicinal Chemistry Letters p. 2891 - 2893 (2003)
Update date:2022-08-03
Topics:
Xia, Yi
Yang, Zheng-Yu
Xia, Peng
Bastow, Kenneth F.
Nakanishi, Yuka
Nampoothiri, Priya
Hamel, Ernest
Brossi, Arnold
Lee, Kuo-Hsiung
2-Phenyl-4-quinolone acetic acids and their esters were synthesized and evaluated for interaction with tubulin and for cytotoxicity against a panel of human tumor cell lines. 2-Phenyl- and 2-(2′-fluorophenyl)-4-quinolone-8- acetic acids (11 and 12) displa
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