Tetrahedron Letters p. 6221 - 6225 (2003)
Update date:2022-08-04
Topics:
Nakamura, Yutaka
Takeuchi, Seiji
Okumura, Kazuo
Ohgo, Yoshiaki
Matsuzawa, Hiroshi
Mikami, Koichi
Asymmetric reduction of a mixture of four fluorous ketone analogues was carried out with (R)-oxazaborolidine as a catalyst. The fluorous mixture products were resolved by a reverse phase HPLC with chiral β-cyclodextrin column to result in good separation of the enantiomers.
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