Synthesis of N-[2-(2-methylpropoxy)ethyl]-N-{2-[(4-methoxy) phenylmethylthio]phenyl}-1-pyrrolidineethanamine (E)-2-butenedioate (1:1) salt (CERM 12816): A potential anti-anginal drug

DOI: 10.1002/(SICI)1099-1344(199803)41:3<181::AID-JLCR68>3.0.CO;2-8

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 181 - 189 (1998)

Update date:2022-08-04

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Authors:

Mounetou, Emmanuelle

Poisson, Claude

Monteil, Andre

Madelmont, Jean-Claude

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Article abstract of DOI:10.1002/(SICI)1099-1344(199803)41:3<181::AID-JLCR68>3.0.CO;2-8

CERM 12816, which was required for metabolic studies, was labelled with [¹⁴C] in the methylene carbon of the benzyl group. This involved eight steps starting from barium [¹⁴C] carbonate and 4-methoxyphenylmagnesium bromide, with a 20

Full text of DOI:10.1002/(SICI)1099-1344(199803)41:3<181::AID-JLCR68>3.0.CO;2-8

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