A facile one-pot synthesis of symmetrical and unsymmetrical acetaldehyde acetals from primary alcohols

Article abstract of DOI:10.1080/00397919208019270

Initial formation of a vinyl ether 2 by treatment of a primary alcohol 1 with ethyl vinyl ether in the presence of mercury (II) acetate followed by treatment with the same or a different alcohol in the presence of p-toluenesulfonic acid affords the symmetrical and unsymmetrical acetaldehyde acetals 3 in good overall yield. The method is easily scaled up and represents a significant improvement over currently available procedures.

Full text of DOI:10.1080/00397919208019270

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Facile One-Pot Synthesis
of Symmetrical and
Unsymmetrical Acetaldehyde
Acetals from Primary Alcohols
Rodney Kiplin Guy a & Richard Anthony DiPietro b
a Research Institute of Scripps, Clinic Department of
Chemistry , 10666 North Torrey Pines Road, La Jolla,
CA, 92037
b K92/801, Almaden Research Center, IBM
Corporation , 650 Harry Road, San Jose, CA,
95120-6099
Published online: 23 Sep 2006.
To cite this article: Rodney Kiplin Guy & Richard Anthony DiPietro (1992) A Facile
One-Pot Synthesis of Symmetrical and Unsymmetrical Acetaldehyde Acetals
from Primary Alcohols, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 22:5, 687-692, DOI:
10.1080/00397919208019270
To link to this article: http://dx.doi.org/10.1080/00397919208019270
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