Hydrobromic acid-dimethyl sulfoxide reagent for dealkylation of 5,10-dialkyl-5,10-dihydrophenazines: Synthesis of 10-alkyl- 2(10H)-phenazinones

Article abstract of DOI:10.1002/jhet.5570360437

By the reaction of 5,10-dialkyl-substituted 5,10- dihydrophenazine with hydrobromic acid in dimethyl sulfoxide at 90-110°, 10-alkyl-2(10H)-phenazinone was obtained as a major product. Brominated dihydrophenazine was isolated in the case of 1,6-dichloro-5,10-dimethyl-5,10-dihydrophenazine.