(Acylaryloxy)acetic Acid Diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic Acids, a New Class of Uricosuric Diuretics

DOI: 10.1021/jm00139a019

Source and publish data:

Journal of Medicinal Chemistry p. 865 - 873 (1981)

Update date:2022-08-05

Topics:

Authors:

Hoffman, William F.

Woltersdorf, Otto W.

Novello, Frederick C.

Cragoe, Edward J

Spinger, James P.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00139a019

The discovery that dihydroethacrynic acid and other (4-acylphenoxy)acetic acids possessed modest but significant uricosuric and diuretic activity prompted our investigation of the related 2,3-dihydro-5-acyl-2-benzofurancarboxylic acids.Synthetic routes to

Full text of DOI:10.1021/jm00139a019

Products guided by the article

Product name:6,7-dichloro-2,3-dihydro-5-(phenylacetyl)-2-benzofurancarboxylic acid

Cas No:62717-23-1

R&D Labs maybe for 62717-23-1

MedicalChem(Yancheng)Manuf.Co.,Ltd.

Contact:+86-515-84383366

Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
Synochem Ingredients Corp., Ltd.

Contact:+86-512-5636 2180

Address:Zhangjiagang Free Trade Zone
Beijing Stable Chemcial Co.ltd

Contact:86-10-63785052

Address:A1301 Technological Edifice. No.4 FuFeng Road,FengTai District, Beijing. China
KODI CHEMICAL CO., LTD

Contact:021

Address:Pudong
Skyrun Industrial Co.,Ltd(expird)

website:http://www.chinaskyrun.com

Contact:0086-576-84610586

Address:Chemical Development Zone

Relevant to this article

H-D Exchange Deuteration of Arenes at Room Temperature

Doi:10.1021/acs.oprd.8b00383
(2019)
Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators

Doi:10.1021/jm0509389
(2006)
Blaise reaction of ethyl 3-bromodifluoromethyl-3-benzyloxyacrylate with nitriles: A convenient synthesis of α-difluorovinyl-substituted β-enaminoesters and β-ketoesters

Doi:10.1055/s-2006-926436
(2006)
A novel indium-catalysed synthesis of tetra-substituted pyridine derivatives

Doi:10.1016/j.tetlet.2003.09.144
(2003)
Synthesis and characterization of new biphenolate and binaphtholate rare-earth-metal amido complexes: Catalysts for asymmetric olefin hydroamination/cyclization

Doi:10.1002/chem.200304975
(2003)
Dopamine D₄ Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy

Doi:10.1021/acs.jmedchem.9b00231
(2019)

Article Doi