(Acylaryloxy)acetic Acid Diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic Acids, a New Class of Uricosuric Diuretics

DOI: 10.1021/jm00139a019

Source and publish data:

Journal of Medicinal Chemistry p. 865 - 873 (1981)

Update date:2022-08-05

Topics:

Authors:

Hoffman, William F.

Woltersdorf, Otto W.

Novello, Frederick C.

Cragoe, Edward J

Spinger, James P.

et al. et al.

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Article abstract of DOI:10.1021/jm00139a019

The discovery that dihydroethacrynic acid and other (4-acylphenoxy)acetic acids possessed modest but significant uricosuric and diuretic activity prompted our investigation of the related 2,3-dihydro-5-acyl-2-benzofurancarboxylic acids.Synthetic routes to

Full text of DOI:10.1021/jm00139a019

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