Functionalized organolithium compounds: Generation via reductive lithiation and nucleophilic addition to N-phenethylimides. Access to functionalized dihydropyrrolo[2,1-a]isoquinolinones

Article abstract of DOI:10.1016/S0040-4020(98)00745-5

A procedure for producing 1,4-dianion equivalents consists of reductive lithiation, induced by 4,4-di-tert-butylbiphenylide, of functionalized phenyl sulfides. Nucleophilic addition of 4-lithio-2-(trimelhylsilylmethyl)but-1- ene 1 and 2-(3-lithiopropyl)-2