Effect of aggregation of nitrile anions on the 1,2 versus 1,4 regioselectivity towards benzylideneacetone

DOI: 10.1016/S0040-4039(00)76706-2

Source and publish data:

Tetrahedron Letters p. 3935 - 3936 (1994)

Update date:2022-08-05

Topics:

Authors:

Strzalko

Seyden-Penne

Wartski Wartski

Froment Froment

Corset Corset

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)76706-2

A direct evidence of the influence of aggregation state of lithiated penylacetonitrile 1 on the 1,2 versus 1,4 regioselectivity towards benzylideneacetone 2 was established. Progressive addition of hexane to THF solutions raised the aggregates proportion of 1 as evidenced by IR ν(CN) band and led to an increase of 1,4 adduct. Monomers afforded 1,2 addition in pure THF.

Full text of DOI:10.1016/S0040-4039(00)76706-2

Products guided by the article

Product name:Benzeneacetonitrile, a-(1-hydroxy-1-methyl-3-phenyl-2-propenyl)-

Cas No:63064-12-0

R&D Labs maybe for 63064-12-0

Taizhou KEDE Chemical.Co.,Ltd.

Contact:86-576-84613060

Address:Jiangkou Chemical Zoon
shanghai payne pharm co.,ltd.

Contact:+86-021-58123769

Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Beijing Top Science biological technology co., LTD

Contact:+86-13439059536

Address:15-1705 jre three mile, Beijing 100000,CHINA
MINS GROUP CO.,LIMITED

Contact:18669908765

Address:Zibo City, Shandong Province, P.R.China
ZHEJIANG NHU COMPANY LTD.

Contact:86-575-86132822，86-575-86085355

Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.

Relevant to this article

Phosphoric esters of adamantanols, adamantanethiols, adamantyl alcohols and their alkyl derivatives, I: Synthese of the phosphoric esters of reaction with 2-chloro-1,3-dioxa-2-phosphorindane-2-oxide (author's transl)

Doi:10.1002/ardp.19773101106
(1977)
Doi:10.1021/jm00218a003
(1977)
Studies on flavans. III. The total synthesis of (±)-7,4′ -dihydroxy-3′-methoxyflavan, (±)-7,3′-dihydroxy-4′ -methoxyflavan, and (±)-7,4′-dihdroxyflavan

Doi:10.1081/SCC-120024733
(2003)
Structure-activity studies of a series of dipyrazolo[3,4-b:3′,4′-d]pyridin-3-ones binding to the immune regulatory protein B7.1

Doi:10.1016/S0968-0896(03)00183-4
(2003)
Doi:10.1021/jo00444a035
(1977)
Bimetallic copper/cobalt-cocatalyzed double aerobic phenol oxidation/cyclization toward π-extended benzofuro[2,3-b]indoles as electron donors for electroluminescence

Doi:10.1039/d1gc01658j
(2021)

Article Doi