Effect of aggregation of nitrile anions on the 1,2 versus 1,4 regioselectivity towards benzylideneacetone

DOI: 10.1016/S0040-4039(00)76706-2

Source and publish data:

Tetrahedron Letters p. 3935 - 3936 (1994)

Update date:2022-08-05

Topics:

Authors:

Strzalko

Seyden-Penne

Wartski Wartski

Froment Froment

Corset Corset

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)76706-2

A direct evidence of the influence of aggregation state of lithiated penylacetonitrile 1 on the 1,2 versus 1,4 regioselectivity towards benzylideneacetone 2 was established. Progressive addition of hexane to THF solutions raised the aggregates proportion of 1 as evidenced by IR ν(CN) band and led to an increase of 1,4 adduct. Monomers afforded 1,2 addition in pure THF.

Full text of DOI:10.1016/S0040-4039(00)76706-2

Products guided by the article

Product name:Benzeneacetonitrile, a-(1-hydroxy-1-methyl-3-phenyl-2-propenyl)-

Cas No:63064-12-0

R&D Labs maybe for 63064-12-0

Beijing Wisdom Chemicals Co., Ltd.

Contact:+86-10-52350335

Address:F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
guide(suzhou) fine materials co. ltd

Contact:0512-80972173

Address:21st Building, No.369 Lushan Rd, New District Suzhou China 215129
Yangzhou Zhongbao Pharmaceutical Co.,Ltd

Contact:+86-514-88290838

Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Shanghai Coupling Pharmaceutical R&D Co., Ltd.(expird)

Contact:+86 021 50106671

Address:403 Room No.4 Buiding, No. 526 Ruiqing Road, Shanghai Zhangjiang Hi-Tech Park
YanCheng LongShen Chemical Co.,Ltd.

Contact:+86-515-86668866

Address:No.13,Weiyi Road,Funing Aoyang Industrial Park

Relevant to this article

Phosphoric esters of adamantanols, adamantanethiols, adamantyl alcohols and their alkyl derivatives, I: Synthese of the phosphoric esters of reaction with 2-chloro-1,3-dioxa-2-phosphorindane-2-oxide (author's transl)

Doi:10.1002/ardp.19773101106
(1977)
Doi:10.1021/jm00218a003
(1977)
Studies on flavans. III. The total synthesis of (±)-7,4′ -dihydroxy-3′-methoxyflavan, (±)-7,3′-dihydroxy-4′ -methoxyflavan, and (±)-7,4′-dihdroxyflavan

Doi:10.1081/SCC-120024733
(2003)
Structure-activity studies of a series of dipyrazolo[3,4-b:3′,4′-d]pyridin-3-ones binding to the immune regulatory protein B7.1

Doi:10.1016/S0968-0896(03)00183-4
(2003)
Doi:10.1021/jo00444a035
(1977)
Bimetallic copper/cobalt-cocatalyzed double aerobic phenol oxidation/cyclization toward π-extended benzofuro[2,3-b]indoles as electron donors for electroluminescence

Doi:10.1039/d1gc01658j
(2021)

Article Doi