Helvetica Chimica Acta p. 2458 - 2470 (2003)
Update date:2022-08-03
Topics:
Gonzalez-Garcia, Eva Maria
Grognux, Johann
Wahler, Denis
Reymond, Jean-Louis
The branched glycerol analogs 1 and 2 were prepared. Mono-ester derivatives of these triols undergo a chromogenic or fluorogenic reaction in the presence of NaIO4. In contrast, both the diesters and the triols are themselves not chromogenic or fluorogenic. Diester derivatives of these triols can be used as probes for lipases. The tris-phosphate derivative of 1 is a fluorogenic substrate for various phosphatases.
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