Folate analogues. 33. Synthesis of folate and antifolate poly-γ-glutamates by [(9-fluorenylmethoxy)oxy]carbonyl chemistry and biological evaluation of certain methotrexate polyglutamate polylysine conjugates as inhibitors of the growth of H35 hepatoma cel

DOI: 10.1021/jm00164a038

Source and publish data:

Journal of Medicinal Chemistry p. 711 - 717 (1990)

Update date:2022-08-05

Topics:

Authors:

Abraham Abraham

Nair Nair

Kisliuk Kisliuk

Gaumont Gaumont

Galivan Galivan

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00164a038

Representative examples of folate and antifolate poly-γ-glutamyl metabolites were synthesized via the [(9-fluorenylmethoxy)oxy]carbonyl (Fmoc) chemistry using the KH polyamide resin. Polyglutamate yields were consistently better in all cases compared to t

Full text of DOI:10.1021/jm00164a038

Products guided by the article

Product name:α-tert-butyl N¹⁰-(trifluoroacetyl)pteroyltriglutamate

Cas No:63948-16-3

R&D Labs maybe for 63948-16-3

Rugao Jinling Chemical Co., Ltd.(expird)

Contact:0086-513-68005586

Address:Lianluo new village huangshi town Rugao city Jiangsu Province.
Huaihua Baohua Biotechnology Co.,Ltd

website:http://www.baochengchem.com

Contact:86-519-82698291

Address:HouYang chemical development zone,Jintan,Jiangsu,China (213200)
Xinjiang Fufeng Biotechnologies Co., Ltd.

Contact:+86-539-7287111

Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
Taizhou Crene Biotechnology co.ltd

Contact:86-576-88813233 88205808

Address:Economic Developed Zone of Taizhou Zhejiang China
SYN Pharma Co., Ltd

Contact:86-21 60347964

Address:No.1304, West Meilong Road, Minhang District, Shanghai, China

Relevant to this article

Doi:10.1021/jo00397a018
(1978)
Synthesis of bis-(3,5)pyrazolophanes via double cycloadditive macrocyclisation

Doi:10.1016/j.tet.2003.09.088
(2003)
A New Reaction Surface for Concerted Reactions: The Metal Ion Catalyzed Addition of Enolpyruvate to Pyruvate

Doi:10.1021/ja00189a028
(1989)
PYRROLES FROM KETOXIMES AND ACETYLENE. 28. INVESTIGATION OF VINYL CHLORIDE INSTEAD OF ACETYLENE FOR THE SYNTHESIS OF ARYLPYRROLES FROM ARYLETHANONE OXIMES

Doi:10.1007/BF00503601
(1984)
A novel synthetic route to 7α-methoxycephalosporins

Doi:10.1248/cpb.27.2718
(1979)
On the alkylation behavior of 2-(phenylseleno) nitriles

Doi:10.1055/s-1997-3212
(1997)

Article Doi