DIOLS AS EFFECTIVE COCATALYSTS IN THE PHASE TRANSFER CATALYZED PREPARATION OF 1-ALKYNES FROM 1,2-DIHALIDES

Article abstract of DOI:10.1016/S0040-4020(01)87322-1

Bis-tertiary diols accelerate bis-eliminations of HX from 1,2-dihalides in the presence of an onium salt as phase transfer catalyst and potassium hydroxyde as base.PEG 400 catalyzes the same elimination, but isomerizations from 1-alkyne to mixtures with the 2-alkyne and the 1,2-diene occur easily.