A New Procedure for the One-Carbon Homologation of Ketones to α-Hydroxy Aldehydes

DOI: 10.1021/jo00182a012

Source and publish data:

Journal of Organic Chemistry p. 1378 - 1382 (1984)

Update date:2022-08-05

Topics:

Authors:

Adamczyk, Maciej

Dolence, E. Kurt

Watt, David S.

Christy, M. Robert

Reibenspies, Joseph H.

Anderson, Oren P.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00182a012

A new, one-carbon homologation procedure for the conversion of ketones to α-hydroxy aldehydes involves two steps: (1) Darzens condensation of ketones with chloromethyl phenyl sulfone; (2) ring opening of the intermediate α,β-epoxy sulfones with hydroxide

Full text of DOI:10.1021/jo00182a012

Products guided by the article

Product name:(2R,3S)-3-Benzenesulfonyl-2-((3aR,5aS,6S,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-2-methyl-oxirane

Cas No:65516-41-8

R&D Labs maybe for 65516-41-8

Hangzhou Taiyan Trading Co., Ltd(expird)

Contact:+86-13777583958

Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
SHANXI JINJIN CHEMICAL INDUSTRIAL CO.,LTD

website:http://www.jinjingroup.com

Contact:86-574-13989382828

Address:Economic And Technological Development Zone,Hejin?City,Shanxi Province?,China
Shanghai Hohance Chemical Co., ltd

Contact:13914753421

Address:Fl.5；Bld. 70, Lane 1500; Xinfei Road
Anhui New Star Pharmaceutical Development Co., Ltd

Contact:013956922763

Address:Floor 3, F9A, F Workshop, No.110 Kexue Road, High-Tech Development Zone, Hefei, Anhui ,China

Relevant to this article

Heterocyclic Compounds with Bridgehead Nitrogen Atoms. Part 8. The Synthesis and Properties of Cyclopenta<4,5>azepino<7,1,2-cd>pyrrolizine (Cyclopenta<2.2.4>cyclazine)

Doi:10.1039/P19800001324
(1980)
Synthesis of the first water-soluble C₂-symmetric bis(oxazolidinone) as a potential bifunctional chiral auxiliary

Doi:10.1016/S0957-4166(00)00086-0
(2000)
Synthesis, structure, and reactivity of ruthenium(II) complexes with a hemilabile tetradentate etherdiphosphine ligand

Doi:10.1016/S0022-328X(00)00065-6
(2000)
Doi:10.1021/jm00299a014
(1970)
An unexpected synthesis of novel oxygen-bridged 1,5-benzothiazepine derivatives and their reductive five-membered-ring opening

Doi:10.1007/s007060050320
(2000)
Reaction of methylpyrimidine derivatives with isoamyl nitrite

Doi:10.1248/yakushi1947.90.7_877
(1970)

Article Doi