REACTION OF N-ACETYLDEHYDROPHENYLALANYL-S-PROLINE WITH Ca(II) AND Ni(II) IONS AND ITS ROLE IN ASYMMETRIC HYDROGENATION

Article abstract of DOI:10.1007/BF00864203

N-Ac-ΔPhe-S-Pro forms strong coordination complexes with the CO2H group of the proline residue and weak coordination complexes through the -C(=O)-N groups with Ca(II) and Ni(II) ions in 95percent aqueous methanol as indicated by the pK_a values,