Synthesis and evaluation of a 5-membered isoiminosugar as glycosidase inhibitor

Article abstract of DOI:10.1016/S0040-4039(98)01157-5

(3R, 4R)-4-hydroxy-3-hydroxymethylpyrrolidine (6) was prepared from D- xylose and found to be a weak inhibitor of α-D-, β-D-glucosidase and α-L- fucosidase.