Synthesis and pharmacological evaluation of some 3-(4-methylphenyl)-2- substituted amino-3H-quinazolin-4-ones as analgesic and anti-inflammatory agents

Article abstract of DOI:10.1002/ardp.200600189

A variety of 3-(4-methyl phenyl)-2-substituted amino-3H-quinazolin-4-ones were synthesized by reacting the amino group of 2-hydrazino-3-(4-methyl phenyl)-3H-quinazolin-4-one with a variety of aldehydes and ketones. The starting material 2-hydrazino-3-(4-m