ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY PURE NATURAL S(+) OR UNNATURAL R(-) DABA

Article abstract of DOI:10.1016/S0040-4039(01)93841-9

After optimization of the reaction conditions, optically pure S(+) DABA is obtained in more than 80percent overall yield.A modell is proposed to explain the dependence of asymmetric induction on the nature of the counter ion (Li(1+), Mg(2+), Bu4N(1+)).