Asymmetric induction in the coupling of 5,6-dihydro-1,4-dithiins with chiral aldehydes. A new synthetic approach to polyhydroxylated compounds

Article abstract of DOI:10.1016/0040-4020(96)00677-1

A new strategy is designed to synthesize polyhydroxyl compounds (and/or carbohydrates) by coupling of 5,6-dihydro-1,4-dithiins - carrying a vinylic hydrogen atom - with chiral aldehydes and, in sequence, stereoselective removal of the dithiodimethylene di