Diastereoselective alkynylation of chiral non-racemic oxazolidines with mixed organoaluminum compounds

DOI: 10.1016/S0040-4039(99)00328-7

Source and publish data:

Tetrahedron Letters p. 2935 - 2938 (1999)

Update date:2022-07-30

Topics:

Authors:

Blanchet, Jerome

Bonin, Martine

Chiaroni, Angele

Micouin, Laurent

Riche, Claude

Husson, Henri-Philippe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)00328-7

A new efficient and scalable route to chiral non-racemic α-substituted propargylamines is described. The reaction pathway consists of the diastereoselective addition of mixed alkynylaluminum reagents to oxazolidines derived from R- (-)-phenylglycinol.

Full text of DOI:10.1016/S0040-4039(99)00328-7

Products guided by the article

Product name:(1R,2R)-2-[(3,4-dimethoxy-benzyl)-(1-methyl-3-phenyl-prop-2-ynyl)amino]-2-phenyl-ethanol

Cas No:668446-50-2

R&D Labs maybe for 668446-50-2

CGeneTech (Suzhou, China) Co., Ltd.

Contact:+86-512-62956962

Address:Room 101，Bld C11,218 Xinghu Rd.,Suzhou industrial Park
Shanghai Pengkai Chemical Co.,Ltd

Contact:+86-21-60526671

Address:No.4226 Duzhuang Rd Minhang District Shanghai China
ANHUI CHEM-BRIGHT BIOENGINEERING CO.,LTD

Contact:86-561-4080321

Address:No.8 Lieshan Industrial Zone of Huaibei
Anhui New Star Pharmaceutical Development Co., Ltd

Contact:013956922763

Address:Floor 3, F9A, F Workshop, No.110 Kexue Road, High-Tech Development Zone, Hefei, Anhui ,China
Ji'an Hairui Natural Plant Co. Ltd.

Contact:0796-8105528

Address:Meilin industry park, Qingyuan district Ji'an City, Jiangxi Province

Relevant to this article

Combinatorial synthesis of structurally diverse triazole-bridged flavonoid dimers and trimers

Doi:10.3390/molecules21091230
(2016)
Direct observation and kinetic characterization of o-quinodimethane and its radical cation variant generated in a photoinduced electron-transfer reaction of 1,2-bis(α-styryl)benzene

Doi:10.1016/j.tetlet.2005.01.124
(2005)
Copper-Catalyzed Coupling of 2-Siloxy-1-alkenes and Diazocarbonyl Compounds: Approach to Multisubstituted Furans, Pyrroles, and Thiophenes

Doi:10.1021/acs.joc.6b00904
(2016)
Copper-catalyzed aerobic oxidative coupling of o-phenylenediamines with 2-aryl/heteroarylethylamines: direct access to construct quinoxalines

Doi:10.1039/c7ob00122c
(2017)
Mechanistic implications of proton transfer coupled to electron transfer

Doi:10.1021/ja000517a
(2001)
Synthesis and properties of push-pull chromophores for second-order nonlinear optics derived from π-extended tetrathiafulvalenes (TTFs)

Doi:10.1016/S0040-4020(02)00803-7
(2002)

Article Doi