Bioorganic and Medicinal Chemistry Letters p. 1415 - 1418 (1999)
Update date:2022-08-05
Topics:
Rodriguez, Chester E.
Lu, Haiyan
Dinh, Trang T.
Mlodnosky, Karyn L.
Dastgah, Azar
Lam, Vinh Q.
Nichols, C. Blake
Berkman, Clifford E.
Several N-thiophosphonyl-glutamates were found to be potent competitive inhibitors of a zinc-dependent glutamyl hydrolase, carboxypeptidase G (CPG). Weak inhibition exhibited by an analogous N-phosphonyl-glutamate suggests that the enhanced potency of the
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