Synthesis of the Proposed Penultimate Biosynthetic Triene Intermediate of Monensin A

DOI: 10.1021/ja00275a055

Source and publish data:

Journal of the American Chemical Society p. 4603 - 4614 (1986)

Update date:2022-07-29

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Authors:

Patel, Dinesh V.

VanMiddlesworth, Frank

Donaubauer, John

Gannett, Peter

Sih, Charles J.

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Article abstract of DOI:10.1021/ja00275a055

A convergent chiral synthesis of the putative biosynthetic triene precursor, 2b, has been accomplished.Our strategy entails the successive assembly of three key chiral synthons, prepared by enzymatic and microbial techniques.

Full text of DOI:10.1021/ja00275a055

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