New chiral ligand for optically active β-Hydroxy esters synthesis by enantioselective reformatsky reactions

Article abstract of DOI:10.1016/S0957-4166(00)86254-0

The cheap commercially available (1S,2S)-1-phenyl-2-amino-1,3-propanediol 2 appears to be a convenient precursor for the synthesis of chiral auxiliaries for the preparation of optically active P-hydroxy esters by asymmetric Reformatsky reactions. The N,N-