AN EASY AND VERSATILE ACCESS TO 8-SUBSTITUTED ISOQUINOLINES

DOI: 10.1016/S0040-4039(00)94711-7

Source and publish data:

Tetrahedron Letters p. 3125 - 3128 (1990)

Update date:2022-08-03

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Authors:

Simig, Gyula

Schlosser, Manfred

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Article abstract of DOI:10.1016/S0040-4039(00)94711-7

Lithiation of N-(2,2-diethoxyethyl)benzylamines and subsequent reaction with electrophiles allow to introduce a variety of carbo- and heterofunctional groups in the ortho-position.Subsequent acid-catalyzed cyclization leads to isoquinolines having an unco

Full text of DOI:10.1016/S0040-4039(00)94711-7

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