Angewandte Chemie - International Edition p. 478 - 482 (2004)
Update date:2022-07-30
Topics:
Kumagai, Naoya
Matsunaga, Shigeki
Shibasaki, Masakatsu
A real step-saver! In a one-step procedure for the synthesis of bicyclic amidines, the azido group is used directly as the nucleophile in the ring-forming reaction. Many functionalized and chiral bicyclic amidines were synthesized in good yield under mild reaction conditions.
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