Synthesis and Complexation Properties of a Water-Soluble Optically Active Cyclophane Incorporating a 4-Naphthyl-1,2,3,4-tetrahydroisoquinoline Unit as a Chiral Spacer

DOI: 10.1021/jo00010a034

Source and publish data:

Journal of Organic Chemistry p. 3362 - 3369 (1991)

Update date:2022-08-02

Topics:

Authors:

Georgiadis, Taxiarchis M.

Georgiadis, Millie M.

Diederich, Francois

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Article abstract of DOI:10.1021/jo00010a034

The unnatural alkaloid 6-methoxy-4-<2-(6-methoxynaphthalenyl)>-1,2,3,4-tetrahydroisoquinoline (5) was prepared as a chiral spacer for optically active cyclophane receptors.Optical resolution of the building block was accomplished through diastereomeric sa

Full text of DOI:10.1021/jo00010a034

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