Journal of the Chemical Society. Chemical communications p. 2511 - 2512 (1994)
Update date:2022-08-03
Topics: Organocatalysis Chiral Catalysts Michael Addition Reactions Dynamic Kinetic Resolution (DKR) Transition Metal-Catalyzed Reactions Multicomponent Reactions (MCRs) Biocatalysis
Bahajaj, Abood A.
Bailey, Patrick D.
Moore, Madeleine H.
Morgan, Keith M.
Vernon, John M.
Bicyclic lactams 14-17 are isomerised on treatment with aluminium trichloride in 1,2-dichloroethane to give spiro lactams in high yield and > 3:1 diastereoselectivity; from the structures of 19a and 22b determined by X-ray crystallography, it follows that
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(1966)
