Tetrahedron Letters p. 8691 - 8692 (1994)
Update date:2022-08-04
Topics:
Van Der Klein, Pieter A. M.
Witkamp, Henk A.
De Vroom, Erik
The reaction of penicillin G I-oxide with BSU followed by treatment with tributyl phosphite gives, after hydrolysis, crystalline thiazoline azetidinone 2. Addition of triethylamine after reduction resulted in the formation of the isomeric thiazoline azetidinone 3.
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