Synthetic Communications p. 137 - 149 (2004)
Update date:2022-07-29
Topics:
Bernabeu, M. Carmen
Diaz, Jose Luis
Jimenez, Oscar
Lavilla, Rodolfo
Starting from a single, commercially available bromoisoquinoline, convenient (multigram) syntheses of 4-substituted-1,2,3, 4-tetrahydroisoquinoline derivatives have been developed. The compounds thus prepared show suitable substitution patterns for further derivatization and constitute a new family of compounds of potential pharmacological interest.
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