A NEO-CLERODANE GLUCOSIDE AND NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM FLAVUM SUBSP. GLAUCUM

Article abstract of DOI:10.1016/S0031-9422(00)85039-6

From the aerial part of Teucrium flavum subsp. glaucum a new neo-clerodane diterpenoid, teuflavin, and a new 19-nor-neo-clerodane glucoside, teuflavoside, have been isolated, besides the previously known diterpene teuflin.The structures of teuflavin (19-acetoxy-4α,18:15,16-diepoxy-6β-hydroxy-3-keto-neo-cleroda-13(16),14-diene-20ξ,12S-hemiacetal) and teuflavoside (18-acetoxy-15,16-diepoxy-19-nor-neo-cleroda-4,13(16),14-trien-20,12S-olid-6β-yl-2-O-acetyl-β-D-glucopyranoside) were established by chemical and spectroscopic means and by correlation with known compounds.In addition, the previously known flavone salvigenin has also been obtained from the same source.Key Word Index - Teucrium flavum subsp. glaucum; Labiatae; diterpenoids; diterpenoid glucoside; neo-clerodane derivatives; teuflavoside; teuflavin; teuflin.