Synthesis p. 97 - 102 (2016)
Update date:2022-07-30
Topics:
Pajtás, Dávid
Patonay, Tamás
Kónya, Krisztina
Simple and convenient synthesis of 8-bromoflavone was achieved, starting from 2-bromophenol through 3′-bromo-2′-hydroxyacetophenone whose preparation was managed to be solved by optimized Fries rearrangement. The Buchwald-Hartwig reaction of 8-bromoflavone with different type of primary and secondary amines was carried out.
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