Tetrahedron p. 1565 - 1570 (1981)
Update date:2022-08-05
Topics:
Seres, J.
Naray-Szabo, G.
Sinom, K.
Daroczi-Csuka, K.
Szilagyi, I.
Parkanyi, L.
Ring transformation of 1-ethoxycarbonyl-3,4-disubstituted maleimide in alkaline solution yielded exclusively 1,5-disubstituted orotic acid.No hydantoin derivatives were detected.These findings can be best explained by assuming that the initial attack of the hydroxylate anion occurs at C2 and not at C5.X-ray diffraction and quantum chemical investigation indicate that stereospecificity is mainly due to through-space electrostatic effects.
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Doi:10.1248/yakushi1947.98.12_1597
(1978)Doi:10.1021/jacs.8b11868
(2019)Doi:10.1016/0031-9422(93)85284-X
(1993)Doi:10.1016/j.bmcl.2015.10.017
(2015)Doi:10.1007/BF00903661
(1980)Doi:10.1016/j.ica.2003.12.006
(2004)
