Tetrahedron Letters p. 6937 - 6940 (1997)
Update date:2022-07-30
Topics:
Kundu, Nitya G.
Khan, M. Wahab
N-Aryl(or, alkyl)-2-iodobenzamides underwent palladium-catalysed reaction with (trimethylsilyl)acetylene to form N-substituted-2-(trimethylsilyl)ethynyl benzamides, which on further Friedel-Crafts acylation and cyclisation yielded Z-3-alkylidene isoindolin-1-ones in a completely regio- and stereoselective manner.
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