Viable use of 2-substituted thiazolidine-4-methanol diastereoisomeric mixtures during asymmetric borane reduction of aromatic ketones

Article abstract of DOI:10.1016/S0957-4166(97)00480-1

The reduction of aromatic ketones by borane in the presence of the inseparable diastereoisomeric mixture of 2-substituted thiazolidine-4- methanol has been investigated. Modest to high enantiomeric excesses were obtained increasing with thiazolidine steri