Novel phosphate ester-linked resins: The solid-phase generation of phenyl phosphate-containing compounds for SH2 inhibition

DOI: 10.1016/S0040-4039(98)00586-3

Source and publish data:

Tetrahedron Letters p. 3435 - 3438 (1998)

Update date:2022-09-26

Topics:

Authors:

Metcalf III, Chester A.

Vu, Chi B.

Sundaramoorthi, Raji

Jacobsen, Virginia A.

Laborde, Edgardo A.

Green, Jeremy

Green, Yinka

Macek, Karina J.

Merry, Taylor J.

Pradeepan, Selvi G.

Uesugi, Mayumi

Varkhedkar, Vaibhav M.

Holt, Dennis A.

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Article abstract of DOI:10.1016/S0040-4039(98)00586-3

An efficient method for the preparation of protected phosphate ester- linked resins in high yield and purity is presented. Variation in tether length/functionality and substitution pattern of the phenol precursors, as well as mild deprotection conditions

Full text of DOI:10.1016/S0040-4039(98)00586-3

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