Two Step Synthesis of Pyridopyrimidines from Acyclic Precursors. Cyclization of 2-Cyanamino-4,6-diphenylpyridine-3-carbonitrile by Hydrogen Halides

DOI: 10.1016/0040-4020(95)00585-V

Source and publish data:

Tetrahedron p. 10253 - 10258 (1995)

Update date:2022-08-04

Topics:

Authors:

Victory, Pedro

Cirujeda, Joan

Vidal-Ferran, Anton

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00585-V

The cyclization of 2-cyanamino-4,6-diphenylpyridine-3-carbonitrile promoted by hydrogen halides takes place regiospecifically leading in all the cases to the 4-amino-2-halogen substituted pyrido<2,3-d>pyrimidine.This procedure completes a flexible and straightforward approach to aromatic pyrido<2,3-d>pyrimidines from acyclic precursors.

Full text of DOI:10.1016/0040-4020(95)00585-V

Products guided by the article

Product name:4-amino-5,7-diphenylpyrido<2,3-d>pyrimidin-2(1H)-one

Cas No:69932-52-1

R&D Labs maybe for 69932-52-1

HANWAYS CHEMPHARM CO.,LIMITED

website:http://www.hanwayschem.com

Contact:+86-18502787239(whatsapp)

Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China
Jiangxi Biochem Co.,Ltd

Contact:86-791-86629460

Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China
Dalian Synco Chemical Co., Ltd.

Contact:+86-411-83635150

Address:Rm 1004, 24, Tangshan Street, Dalian
Hangzhou GreenCo Science & Technology Co., Ltd.

Contact:86-571-88257303

Address:1713 Room,Jingui Building,Gudun Road,Xihu District,Hangzhou,China
Devepharma Laboratories Ltd

Contact:0086 13585563621

Address:Suite 302, Block B2, Building #19, No. 528 Ruiqing Rd. Pudong, Shanghai 201201, China

Relevant to this article

3,5-Dibromophenyl-functionalised imidazolium salts and their corresponding [Au(NHC)₂]⁺ complexes: synthesis, supramolecular chemistry and anti-cancer activity

Doi:10.1007/s10847-021-01082-6
(2021)
Metal-chelating properties and antiviral activity of some 2-hydroxyphenyl amides

Doi:10.1016/j.poly.2017.03.032
(2017)
Conversion of alkyl- and arylallenes into 1-alkynes through metallated intermediates

Doi:10.1080/00397919708005448
(1997)
3,5-Dialkyl effect on enantioselectivity in Pd chemistry: Applications involving both bidentate and monodentate auxiliaries

Doi:10.1021/om034381b
(2004)
Doi:10.1021/ja00501a036
(1979)
Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase/ butyrylcholinesterase and modulators of Ca²⁺ channels and nicotinic receptors

Doi:10.1016/j.bmc.2004.02.017
(2004)

Article Doi