Synthesis and Some Pharmacological Properties of Z-Tyr(SO3H)-Met-Gly-Trp-Met-Asp(Phe-NH2)-OH, a 32-β-Aspartyl Analogue of Cholecystokinin (Pancreozymin) 27-33

Article abstract of DOI:10.1021/jm00347a019

The heptapeptide carbobenzoxy-L-tyrosyl(O-sulfate)-L-methionylglycyl-L-tryptophyl-L-methionyl-L-aspartyl-β-L-phenylalanine amine (Z-32-β-Asp-CCK-27-33) was synthesized and tested for its ability to stimulate amylase secretion from dispersed pancreatic aci