
Chemical and Pharmaceutical Bulletin p. 680 - 684 (1993)
Update date:2022-07-30
Topics:
Akita
Umezawa
Takano
Oishi
The reaction of (±) methyl 4,5-trans-epoxy-(2E)-hexenoate (1) with nucleophiles having heteroatoms in the presence of BF3 · Et2O gave the 4,5-anti-5-hydroxy-4- and/or 2,5-anti-5-hydroxy-2-substituted products. Among them, the (±)-4,5
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