
Journal of the Chemical Society. Perkin transactions I p. 2323 - 2327 (1990)
Update date:2022-07-30
Topics:
Carruthers, William
Coggins, Peter
Weston, John B.
The usefulness of the cycloaddition of alkenes to 2-alkyl-2,3,4,5-tetrahydropyridine oxides for the preparation of trans-2,6-dialkylpiperidines is confirmed by a stereoselective synthesis of (+/-)-andrachamine.Peroxy acid oxidation of 9-oxa-1-azabicyclo<4.3.0>nonanes does not lead regioselectively to the corresponding 2-alkyl-2,3,4,5-tetrahydropyridine oxide, as had previously been claimed.
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