Journal of Medicinal Chemistry p. 1465 - 1471 (1981)
Update date:2022-08-04
Topics:
Closse, Annemarie
Haefliger, Walter
Hauser, Daniel
Gubler, Hans Ulrich
Dewald, Beatrice
Baggiolini, Marco
A series of 2,3-dihydrobenzofuran-2-one analogues of the mold metabolite wortmannin, which is a powerful antiimflammatory compound, was synthesized.Most of these compounds were tested for their ability to inhibit the carrageenin paw edema and the adjuvant
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