Journal of Medicinal Chemistry p. 98 - 100 (1980)
Update date:2022-08-04
Topics:
Anderson, Neal G.
Carson, John R.
5-(4-Chlorobenzoyl)-4-(hydroxymethyl)-1-methyl-1H-pyrrole-2-acetic acid (2), the major oxidative metabolite of zomepirac (1), was synthesized starting with ethyl 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate (3), the ethyl ester of 1.Compound 3 wa
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