Oxytocin and Lysine-vasopressin with N5,N5-Dialkylglutamine in the 4 Position: Effect of Introducing Sterically Hindered Groups into the Hydrophilic Cluster of Neurohypophyseal Hormones

DOI: 10.1021/jm00176a020

Source and publish data:

Journal of Medicinal Chemistry p. 213 - 217 (1980)

Update date:2022-08-05

Topics:

Authors:

Stahl, Glenn L.

Smith, Clark W.

Walter, Roderich

Tsegenidis, theodor

Stavropoulos, George

et al. et al.

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Article abstract of DOI:10.1021/jm00176a020

The synthesis and pharmacological potencies of oxytocin and lysine-vasopressin analogues are reported in which the N⁵-amide of their glutaminyl residues are dialkylated.These analogues have been studied as an ongoing exploration of the biologic

Full text of DOI:10.1021/jm00176a020

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