The reaction of ninhydrin with trimethylbenzenes under Friedel-Crafts reaction conditions

Article abstract of DOI:10.1080/00397910008087123

The reaction of ninhydrin with 1,2,3- and 1,2,4-trimethylbenzene in the presence of H₂SO₄ or AlCl₃ afforded 2-monoaryl and 2,2-diaryl-1,3- indanedione derivatives as the major products. With 1,3,5-trimethylbenzene as the arene nucleophile, either a reduction product or an indenoindanone derivative was obtained depending upon the catalyst employed in the reaction.

Full text of DOI:10.1080/00397910008087123

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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The Reaction of Ninhydrin
with Trimethylbenzenes
under Friedel-Crafts Reaction
Conditions
Hyun Nam Song a , Hong Jung Lee a , Mi Ra Seong b
Keum Shin Jung b & Jae Nyoung Kim a
,
a Department of Chemistry , Chonnam National
University , Kwangju, 500-757, Korea
b Central Research Institute, Hanmi Pharmaceutical
Co. Ltd. , 371, Sampyoung-dong, Sungnam, Kyonggi-
Do, 463-400, Korea
Published online: 04 Dec 2007.
To cite this article: Hyun Nam Song , Hong Jung Lee , Mi Ra Seong , Keum Shin Jung
& Jae Nyoung Kim (2000) The Reaction of Ninhydrin with Trimethylbenzenes under
Friedel-Crafts Reaction Conditions, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 30:6, 1057-1066,
DOI: 10.1080/00397910008087123
To link to this article: http://dx.doi.org/10.1080/00397910008087123
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