Enantioselective synthesis of Epi-emetine analogues: Control of the facial selectivity in a three-component domino Knoevenagel-hetero-Diels-Alder reaction

DOI: 10.1515/znb-2004-0415

Source and publish data:

Zeitschrift fur Naturforschung, B: Chemical Sciences p. 468 - 477 (2004)

Update date:2022-08-03

Topics:

Authors:

Tietze, Lutz F.

Rackelmann, Nils

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Article abstract of DOI:10.1515/znb-2004-0415

The domino Knoevenagel-hetero-Diels-Alder reaction of the aldehyde rac-8, Meldrum's acid 2 and enol ether 3 leads to the cycloadduct rac-17 as the main product which in a second domino process was transformed into the benzoisoquinolizidine rac-18 by solvo

Full text of DOI:10.1515/znb-2004-0415

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